ANTIMICROBIAL RESISTANCE: CONTEMPORARY CHALLENGES FOR THE PREVENTION AND CONTROL OF HEALTHCARE-ASSOCIATED INFECTIONS

Authors

  • Neila Regina de Oliveira Montingelli
  • Marcio Alexandre Botti
  • Vitor Prata Oliveira Amaral
  • Paula Steger
  • Jussara Cassandra Morais Cavalcanti

DOI:

https://doi.org/10.63330/sasciencesv6n2-246

Keywords:

Antimicrobial resistance, Antimicrobials, Healthcare-associated infections, Infection control, Patient safety

Abstract

Antimicrobial resistance  ontrolo f  one of the major contemporary challenges for the prevention and  ontrolo f healthcare-associated infections, particularly because it reduces treatment effectiveness and increases the complexity of care for patients affected by resistant microorganisms. This study is characterized as a literature review with a qualitative and descriptive-analytical approach and aims to analyze the main factors associated with antimicrobial resistance in healthcare settings, as well as the strategies used to prevent its spread and strengthen infection control. The methodology is based on the analysis of scientific publications and technical-scientific documents related to antimicrobial use, resistance mechanisms, infection prevention, and patient safety. The findings indicate that inappropriate and excessive antimicrobial use, failures in infection prevention and control practices, and the spread of resistant microorganisms contribute to the persistence of the problem in healthcare services. It is concluded that addressing antimicrobial resistance requires integrated actions, including rational antimicrobial use, microbiological surveillance, appropriate hand hygiene, adoption of precautions, continuing education of healthcare teams, and strengthening of infection prevention and control programs.

Downloads

Download data is not yet available.

References

ALLEGRANZI, Benedetta; PITTET, Didier. Role of hand hygiene in healthcare-associated infection prevention. Journal of Hospital Infection, v. 73, n. 4, p. 305–315, 2009. DOI: 10.1016/j.jhin.2009.04.019.

ANTIMICROBIAL RESISTANCE COLLABORATORS. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. The Lancet, v. 399, n. 10325, p. 629–655, 2022. DOI: 10.1016/S0140-6736(21)02724-0.

BARLAM, Tamar F.; COSGROVE, Sara E.; ABBO, Lilian M.; MACDOUGALL, Conan; SCHUETZ, Audrey N.; SEPTIMUS, Edward J.; SRINIVASAN, Arjun; DELLIT, Timothy H.; FALCK-YTTER, Yngve T.; FISHMAN, Neil O.; HAMILTON, Cindy W.; JENKINS, Timothy C.; LIPSETT, Pamela A.; MALANI, Preeti N.; MAY, Larissa S.; MORAN, Gregory J.; NEUHAUSER, Melinda M.; NEWLAND, Jason G.; OHL, Christopher A.; SAMORE, Matthew H.; SEO, Susan K.; TRIVEDI, Kavita K. Implementing an antibiotic stewardship program: guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America. Clinical Infectious Diseases, v. 62, n. 10, p. e51–e77, 2016. DOI: 10.1093/cid/ciw118.

BURNETT, Edward. Effective infection prevention and control: the nurse's role. Nursing Standard, v. 33, n. 4, p. 68–72, 2018.

MOUAJOU, V.; ADAMS, K.; DELISLE, G.; QUACH, C. Hand hygiene compliance in the prevention of hospital-acquired infections: a systematic review. Journal of Hospital Infection, v. 119, p. 33–48, 2022. DOI: 10.1016/j.jhin.2021.09.016.

STORR, Julie; TWYMAN, Anthony; ZINGG, Walter; DAMANI, Nizam; KILPATRICK, Claire; REILLY, Jacqui; PRICE, Lesley; EGGER, Matthias; GRAYSON, M. Lindsay; KELLEY, Edward; ALLEGRANZI, Benedetta. Core components for effective infection prevention and control programmes: new WHO evidence-based recommendations. Antimicrobial Resistance & Infection Control, v. 6, art. 6, 2017. DOI: 10.1186/s13756-016-0149-9.

WEINSTEIN, Robert A. Controlling antimicrobial resistance in hospitals: infection control and use of antibiotics. Emerging Infectious Diseases, v. 7, n. 2, p. 188–192, 2001. DOI: 10.3201/eid0702.700188.

WORLD HEALTH ORGANIZATION. Global action plan on antimicrobial resistance. Geneva: World Health Organization, 2015.

WORLD HEALTH ORGANIZATION. Guidelines on core components of infection prevention and control programmes at the national and acute health care facility level. Geneva: World Health Organization, 2016.

WORLD HEALTH ORGANIZATION. Global report on infection prevention and control 2024. Geneva: World Health Organization, 2024. 210 p. ISBN 978-92-4-010398-6.

Downloads

Published

2026-10-21

How to Cite

Montingelli, N. R. de O. ., Botti, M. A. ., Amaral, V. P. O. ., Steger, P. ., & Cavalcanti, J. C. M. . (2026). ANTIMICROBIAL RESISTANCE: CONTEMPORARY CHALLENGES FOR THE PREVENTION AND CONTROL OF HEALTHCARE-ASSOCIATED INFECTIONS. South American Sciences, 6(2), e26473. https://doi.org/10.63330/sasciencesv6n2-246

Issue

Vol. 6 No. 2 (2026): South American Sciences

Section

Artigos

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Autores concordam com os seguintes termos:

a) Os autores mantêm os direitos autorais e concedem à revista o direito de primeira publicação, com o trabalho simultaneamente licenciado sob a LicençaAttribution-NonCommercial-ShareAlike 4.0 International, que permite o compartilhamento do trabalho com reconhecimento da autoria e publicação inicial na Revista SAS. A licença permite o uso, a distribuição e a reprodução irrestrita, em qualquer meio, desde que devidamente citada a fonte. Essa licença permite também que outros remixem, adaptem e criem a partir do seu trabalho para fins não comerciais, desde que atribuam a você o devido crédito e que licenciem as novas criações sob termos idênticos.

b) Não cabe aos autores compensação financeira a qualquer título, por artigos ou resenhas publicados na South American Sciences.

c) Os conceitos expressos nos artigos publicados na South American Sciences são de inteira responsabilidade de seus autores.

Most read articles by the same author(s)